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CAS No. 108885-68-3 | Taccalonolide A

Name: Taccalonolide A CAS No. 108885-68-3 MF:C36H46O14 MW:702.74 Purity:98% Package: 10mg,25mg,50mg,100mg,250mg Worldwide Delivery

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Analytical Chemicals

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Product introduction

Introduction and application of CAS No. 108885-68-3 | Taccalonolide A

Synonyms:(1alpha,2alpha,3alpha,5alpha,7beta,11alpha,12alpha,15alpha,16beta,24beta,25S)-1,11,12,15-Tetrakis(acetyloxy)-2,3-epoxy-7,23,25-trihydroxy-6-oxo-16,24-cycloergost-22-en-26-oicacidgamma-lactone;

16,24-Cycloergost-22-en-26-oicacid,1,11,12,15-tetrakis(acetyloxy)-2,3-epoxy-7,23,25-trihydroxy-6-oxo-,γ-lactone,(1α,2α,3α,5α,7β,11α,12α,15α,16β,24β,25S)-;

Microtubule/Tubulin,Apoptosis,inhibit,Inhibitor,TaccalonolideA

Specification:

ITEMS	SPECIFICATION
CAS	108885-68-3
MF	C36H46O14
MW	702.74
Melting point	776.8±60.0 °C
Density	1.41±0.1 g/cm3
Acidity coefficient	11.56±0.70
Solubility	Soluble in dimethyl sulfoxide
Storage condition	Store at -20°C

Biological activity:

TaccalonolideA is a microtubule stabilizer, a steroid isolated from Taccachantrieri, with cytotoxic and antimalarial activity. TaccalonolideA can cause G2-M phase retention, Bcl-2 phosphorylation, and trigger cell apoptosis. TaccalonolideA has a significant inhibitory effect on cell lines overexpressing p-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7) in vitro. The IC50 value of inhibiting the growth of SK-OV-3 cells is 622nM.

Package and transportation :

Package: 10mg,25mg,50mg,100mg,250mg